Cystic Fibrosis (CF): Delivered following a bronchodilator, hypertonicsodium chloride 7% appears inexpensive and safe with no increasedinfection risk. A Cochrane review stated that there is sufficientevidence to recommend using hypertonic sodium chloride 7% inthose with CF (Wark 2009) (Elkins 2006). Approved in accordance with NHS England ClinicalCommissioning UrgentPolicy Statementsfor the treatment ofcystic fibrosis in patients 6 years and older with named mutations. Usedin combination with ivacaftor. PULMOCLEAR Inhalation Solution is used for moistening the upper and lower respiratory passages by spraying with an electrically operated jet nebuliser or ultrasonic nebuliser; e.g. as a supplementary measure for the treatment of colds (e.g. cough or head cold), reduced humidity typical of spending long periods in air-condtioned or heated rooms. Grey / Non-Formulary: Medicines, which the Nottinghamshire APC has actively reviewed and does not recommend for use at present due to limited clinical and/or cost effective data. Preferred brands in primary care are PulmoClear ® 0.9%, Salineb 0.9%, Knoxzy 0.9% or Respi-Clear ® 0.9%. See Preferred Prescribing List

The time taken for this medicine to show its effect is subject to vary based on the intended use and form of medicine consumed.This medicine is not recommended for use by pregnant women. Consult your doctor immediately if a pregnancy is suspected while taking this medicine. Bronchiectasis: British Thoracic Society Guidelines for the treatment of non-CF bronchiectasis suggest that hypertonic sodium chloridemay be considered for use prior to airway clearance to increasesputum yield, reduce sputum viscosity and improve ease of expectoration (BTS July 2010). Ans : This medication should be consumed till complete eradication of disease, so it is advised to use till the time directed by your doctor. PULMOCLEAR Inhalation Solution is not subject to any age limit restrictions and may therefore also be administered to small children.

Ans : Pulmoclear is a xanthine derivative. It contains Acebrophylline and AcetylCysteine as active ingredients.

Frequently Asked Questions (FAQs)

Grey / Non-Formulary (no formal assessment): APC has not formally reviewed this medicine or indication because it had never been requested for formulary inclusion. Often used for drugs new to market. Pulmoclear Tablet can be taken with or without food. Your doctor will decide the dose and duration of this medicine based on the type and severity of your medical condition. Take this medicine as directed by your doctor. Do not stop taking this medicine without consulting your doctor as this could lead to worsening your condition.

Pulmoclear Tablet shows some common side effects like heartburn, fever, nausea, vomiting, rash, irritation and swelling of the nasal passages (pathway from the nose to throat). Consult your doctor if any of these side effects do not resolve or worsen. Avoid taking this medicine if you are allergic to it. Ans : Dizziness, drowsiness, chest tightness, cough, and epigastric tenderness, etc are common side effects.

Find in store

Pulmoclear Hypertonic Sodium Chloride Solution is formulated in three different strengths: 3%, 6%, and 7%. This solution is specially designed to mobilize lower respiratory tract secretions, providing relief from congestion and facilitating easier breathing. By preventing the drying of bronchial mucous, it helps maintain a healthy respiratory system. Whether you’re suffering from a common cold, allergies, or chronic respiratory conditions, Pulmoclear Hypertonic Sodium Chloride Solution can be your go-to solution. It was found that Hypertonic Saline inhaled twice per day reducedepisodes of chest infection and was linked to lung function andquality of life improvement, and better attendance at school or work. Ambroxol theophyllinacetate- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 09 May 2019]. Available from:

Grey / Non-Formulary (undergoing assessment): Work is ongoing and will be reviewed at a future APC meeting. The Pulmocare supplement strengthens respiratory muscles and boosts the energy required for the respiration processFor nebulisation (unlicensed use, not recommended) - Use 1-5mL of 20% injection, diluted up to 5ml with normal saline, TDS. (Higher doses less tolerable). Precede with salbutamol as may cause bronchoconstriction. No conclusive proof of efficacy has yet been found. On the other hand, Pulmoclear Isotonic Saline Solution is a sterile Sodium Chloride 0.9% inhalation solution. This solution is specifically formulated for respiratory tract humidification, ensuring optimal moisture levels in the airways. It is suitable for individuals of all ages and can be used to alleviate symptoms of dryness, irritation, and discomfort caused by various respiratory conditions. Pulmoclear Syrup is a combination medicine used in the treatment of cough with mucus. It thins mucus in the nose, windpipe and lungs, making it easier to cough out. It also provides relief from runny nose, sneezing, itching, and watery eyes. Nottingham and Nottinghamshire ICB, Greener Inhaler Alternatives Medicines Optimisation Toolkit for ADULTS