Thiazide diuretics reduce the urinary excretion of calcium. Due to an increased risk of hypercalcaemia, serum calcium should be regularly monitored during concomitant use of thiazide diuretics. Rennie should not be used in patients with hypercalciuria (see also section 4.3). Prolonged use increases the risk of formation of renal calculi.

Rennie Antacids, Spearmint Flavour, 72 Count (Pack of 1) Rennie Antacids, Spearmint Flavour, 72 Count (Pack of 1)

It has been shown that antacids which contain calcium or magnesium may form complexes with certain substances e.g. antibiotics (such as tetracyclines and quinolones), and cardiac glycosides (e.g. digoxin), bisphosphonates, dolutegravir, levothyroxine, and eltrombopag, resulting in decreased absorption. This should be borne in mind when concomitant administration is considered. Calcium salts reduce the absorption of fluorides and iron-containing products, and calcium salts and magnesium salts can hinder the absorption of phosphates. In vitro acid neutralisation studies (artificial stomach model) showed that Rennie increases stomach pH from pH 1.5-2 to pH 3 in 40 seconds and is able to reach pH 4 in 1 minute 13 seconds. The maximum level of pH achieved in the model was pH 5.24.

Especially in patients with impaired renal function, prolonged use of high doses can result in hypermagnesaemia or hypercalcaemia and alkalosis which may give rise to gastric symptoms and muscular weakness (see below). Hypersensitivity reactions have very rarely been reported. Clinical symptoms may include rash, urticaria, pruritus, angioedema, difficulty in breathing and anaphylaxis. If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4. Calcium and magnesium are excreted in human milk, but at therapeutic doses of the product no effects on the breastfed newborns/infants are anticipated.

Rennie Peppermint 96s - Savers Rennie Peppermint 96s - Savers

Changes in gastric acidity, such as that caused by the ingestion of antacids, can affect the rate and degree to which some concurrently administered medicines are absorbed. Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. The stated dose should not be exceeded. If, after 14 days of treatment, symptoms persist or only partly disappear the patient should consult a doctor. Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity.A small amount of calcium and magnesium may be absorbed, but in healthy subjects is usually rapidly excreted by the kidney.

Rennie Spearmint 96s - Savers

Calcium carbonate has a rapid and powerful neutralising action. This effect is increased by the addition of magnesium carbonate which also has a strong neutralising action. The maximum recommended daily dose should not be exceeded and should not be taken for more than 2 weeks. If symptoms persist or only partly disappear after 2 weeks, medical advice should be sought. If you are taking any of the following medicines speak to your doctor or pharmacist before taking Rennie Peppermint because it can affect how these medicines work.If you are taking any of the following medicines speak to your doctor or pharmacist before taking Rennie Spearmint because it can affect how these medicines work.