Young, healthy adults. Those without health issues who are under 40 are at very low risk for a CoQ10 deficiency. Fragaki, K., et al. (2016). Coenzyme Q10 defects may be associated with a deficiency of Q10-independent mitochondrial respiratory chain complexes. Emami A & Bazargani-Gilani B. (2018). Effect of oral CoQ 10 supplementation along with precooling strategy on cellular response to oxidative stress in elite swimmers.

When used alone or in combination with other nutrients, such as magnesium and riboflavin, CoQ10 has been shown to improve migraine symptoms. Zozina, V., et al. (2018). Coenzyme Q10 in cardiovascular and metabolic diseases: Current state of the problem.CoQ10 is equally well-studied in competitive athletes and in people with serious health conditions, like chronic heart failure. How we ranked For those who’re serious about taking the most potent CoQ10, Live Conscious CoQ10 is the best you can get. CoQ10 plays a fundamental role in energy production and acts as a powerful antioxidant, inhibiting free radical generation and preventing cell damage ( 4). Likewise, other research found that CoQ10 supplementation could boost ovary function and extend the longevity of high-quality eggs in women ( 10 ). Statin drugs can deplete CoQ10 stores, and one way to help your body replenish is with a CoQ10 supplement. While more research is needed, CoQ10 supplements may also help with some side effects of statin drugs. A 2018 study found that CoQ10 supplement may reduce statin-associated muscle symptoms including muscle pain, weakness, cramps, and tiredness.

CoQ-10 (Coenzyme Q-10) 200 mg Vegetable Capsules contains KanekaQ10 ®, a patented form of CoQ10 fermented from yeast and bio-identical to the CoQ10 which is produced by the body.CoQ10 supplements are considered safe for most people with a relatively low risk for any side effects. The side effects that have been reported—insomnia and digestive upset—are mild and usually reported with higher doses. Breaking up dosage throughout the day can help. Under normal conditions, free radicals regulate communication between cells and defend the body against infectious microbes. However, excess free radicals cause DNA damage, which can lead to the following: Chai W, et al. (2011). Plasma coenzyme Q10 levels and prostate cancer risk: the multiethnic cohort study. Abnormal mitochondrial function can reduce muscle energy, making it hard for muscles to contract efficiently and sustain exercise.

The bulk of scientific research studies use doses of 150 to 200 milligrams of coenzyme Q10, suggesting that the optimal dose for both cognitive and physical function lies within this range. What’s more, those with diabetes may have lower levels of CoQ10, and certain anti-diabetic drugs may further deplete body stores of this important substance ( 26).

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One thing to note is this supplement doesn’t have an absorption enhancer, which means you should take it with or after a meal that has healthy fat sources to ensure optimal absorption. Similarly, male sperm is susceptible to oxidative damage, which may result in reduced sperm count, poor sperm quality, and infertility. Supplementing with CoQ10 appears to be well tolerated by humans, even when used in doses up to 1,200 mg. However, it’s best to use it only as directed. Though these drugs are generally well tolerated, they can cause adverse side effects, such as serious muscle injury and liver damage. Easily a top 3 option and also one of the cheapest options on this list. 4. Transparent Labs Raw Series CoQ10