Smecta is sold over the world in pharmacies. The manufacturer of the drug is the French pharmaceutical company “Bofour Ipsen Industry”. Smecta has analogues with similar indications. Usually they have the same active substance – dioctahedral smectite. These drugs include Neosmectin and Diosmectin. Other sorbents, for example, activated carbon, are indirect analogues. However, it should be understood that not all sorbents are as effective and selective in their action as Smecta. Indications for use, contraindications and side effects In adults, no prospective, randomized, placebo-controlled trial on the efficacy of diosmectite in the treatment of acute diarrhoea has yet been conducted. Diosmectite was compared to loperamide only, in four open, prospective trials that showed similar effects for both drugs in the treatment of acute infectious diarrhoea [ 11– 14]. The clinical effect of diosmectite has nonetheless been studied in functional diarrhoea [ 15, 16], radiation-induced diarrhoea [ 17], irinotecan-induced diarrhoea [ 18], and AIDS-associated chronic idiopathic diarrhoea [ 19]. An allergic reaction that can manifest itself by the following signs: redness of the skin, itching, swelling of the face and throat, difficulty breathing, malaise, collapse.

Taking an excessively high dose of SMECTA 3 g ORANGE-VANILLA can cause constipation, which generally disappears when the dose is decreased or treatment is stopped. Consult your doctor or pharmacist.If you have acute diarrhea due to an infection, consider using the right antibiotic so that you can completely treat the cause. Flow chart of study populations. Diosmectite (6g three times a day) or placebo in the treatment of acute diarrhoea in adults. to the last day of that month. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment. Smecta drug does not have any indication for pregnant and lactating women. Therefore, before using, you should consult your doctor to weigh the benefits and risks of the drug.

Sample size determination was based on the hypothesis that time to recovery was significantly shorter under diosmectite than under placebo (one-sided hypothesis). From previous studies, the expected difference of the primary efficacy criterion between diosmectite and placebo was 24 hours, with an estimated standard deviation (SD) of 61.7 hours. With an alpha risk of 5% and a beta risk of 20%, the number of patients to be included per group was 140 to obtain 104 “assessable” patients per group, that is, for which the primary outcome could be assessed. Smecta is used for diarrhea, food and alcohol poisoning, relieving hangover, nausea, dyspepsia, vomitting, flatulence. Smecta has some contraindications. First of all, the drug should be taken with caution with a tendency to constipation. In the presence of intestinal obstruction or severe chronic constipation, admission is directly contraindicated. You should also not take medicine in case of intolerance to its components. Continue feeding during diarrhea, excluding certain foods, especially raw vegetables and fruits, green vegetables, spicy dishes, as well as frozen foods or drinks,For babies and children, Smecta ® should be taken in addition to an oral rehydration solution. For chronic diarrhoea in adults, the dosage is of an average of 3 sachets per day. Precautionary measures DRUG INTERACTIONS (summary) This drug may decrease the absorption of many drugs. A delay of at least 2 hours (or even 4 hours with antibiotics of the quinolone family) must be observed between taking this drug and that of other treatments. Ask your doctor or pharmacist. To avoid reducing the efficacy of the other treatments, you should take Smecta ® separately (at least 2 hours of distance).

Although Smecta diarrhea medicine is quite benign, it is still unavoidable with some side effects for some cases such as: Antibiotics can alter the digestive flora, essential for digestion, and cause more or less troublesome but benign diarrhea. The effect appears immediately or after a few days of treatment. A severe and exceptional form of diarrhea, pseudomembranous colitis, can be observed after antibiotic treatment; this condition results in the emission of mucus and false membranes (resembling skin flaps) associated with abdominal pain; constipation may replace the initial diarrhea. Pseudomembranous colitis can occur several days after discontinuation of antibiotic treatment and requires urgent medical advice. Smecta works by mechanism to create a covering film to cover the lining of the digestive tract and prevent the adhesion of factors that cause diarrhea. That is the reason why medications can alter the way some other drugs work. The substances contained in this medication are poorly absorbed. However, do not use it for a prolonged period during pregnancy or breastfeeding without the advice of your doctor or pharmacist. Avoid use of Smecta ® in infants and children aged below 2 years old. The reference treatment in acute diarrhoea is oral rehydration salts (ORS).You should space the intake of SMECTA 3 g ORANGE-VANILLA from another medication of more than 2 hours, if possible. Many medicines can accelerate intestinal transit and make the stools more liquid, without this undesirable effect being of real concern. Smecta adalah obat antidiare yang di produksi oleh Combiphar. Smecta mengandung Dioctahedral smectite yang diindikasikan untukmengobati gejala pada diare non spesifik. Keterangan Therefore, before using Smecta, the patient should make a list of the medicines you are using for the doctor or pharmacist. To ensure safety when using, you should not arbitrarily take the drug, stop or change the dosage without the permission of your doctor. Before using Smecta Sachet Powder, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.