Joined in 2023 
82 
63 About this deal
Chu, “Low-dose curcumin leads to the inhibition of tumor growth via enhancing CTL-mediated antitumor immunity,” International Immunopharmacology, vol.
Turmeric improves the glutathione (GSH) synthesis in experimental models, thus reducing the free radical damage and indeed oxidative stress. It seems that curcumin targets the spindle assembly checkpoint to initiate apoptosis in the cells having higher concentration of phosphorylated cell division cycle 27 (CDC27). Nejatbakhsh, “A comparative study of ranitidine and quince ( Cydonia oblonga mill) sauce on gastroesophageal reflux disease (GERD) in pregnancy: a randomised, open-label, active-controlled clinical trial,” Journal of Obstetrics and Gynaecology, vol. Why It's Worth It: This thoughtful serum deploys tetrahexyldecyl (often shortened to THD) ascorbate — which is a very stable form of vitamin C — to minimize signs of dark spots, lines, wrinkles, and loss of elasticity.M. Srinivas Bharath, “Chronic dietary supplementation with turmeric protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-mediated neurotoxicity in vivo: implications for Parkinson's disease,” British Journal of Nutrition, vol.
To incorporate turmeric into your diet, add it to curries, soups, or smoothies, or take a turmeric supplement. Turmeric is good for your skin, and infusing it in your serum is one of the best decisions you’ll make.It also subdues NF- κB activation initiated by receptor activator of nuclear factor-kappa B ligand (RANKL), which may be associated with the repression of osteoclastogenesis. This is because serums contain potent actives like niacinamide, retinol, vitamin C, and hyaluronic acid that address various skin concerns. Results of a study on a novel intravenously injectable curcumin revealed that rabbits in curcumin nanosuspension group developed local irritation and phlebitis risks and erythrocyte hemolysis lesser than those in curcumin solution group [ 139]. However, there is a report stating that oral curcumin about 1000 mg/kg body weight can cause a slight reduction of weight gain in F2 generation chicks [ 131]. Sahebkar, “Medicinal plants in traumatic brain injury: neuroprotective mechanisms revisited,” BioFactors, vol.
Apoptotic death in curcumin-treated NPC-TW 076 human nasopharyngeal carcinoma cells is mediated through the ROS, mitochondrial depolarization and caspase-3-dependent signaling responses,” International Journal of Oncology, vol. Turmeric performs antitumor and anticancer functions through the inhibition of NF- κB establishment and downregulation of NF- κB-related gene products associated with endurance, propagation, and metastasis of cancer cells. In addition, it can make a balance between extracellular matrix components’ synthesis and degradation [ 123– 125]. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. A schematic diagram representing turmeric’s medicinal attributes regarding some of the most important mechanisms.
Sodium hyaluronate, a cross-linked form of hyaluronic acid, helps boost the efficacy of HA to attract and lock moisture in the skin. V. Kumar, “Purely aqueous PLGA nanoparticulate formulations of curcumin exhibit enhanced anticancer activity with dependence on the combination of the carrier,” International Journal of Pharmaceutics, vol. It has been shown that oxidative stress and distressed protein metabolism and their interaction are central to AD pathogenesis [ 107]. The authors thank the Library Department, Government College University Faisalabad (GCUF), and IT Department, Higher Education Commission (HEC), for the access to journals, books, and valuable database. Feria-Velasco, “Curcumin protects against the oxidative damage induced by the pesticide parathion in the hippocampus of the rat brain,” Nutritional Neuroscience, vol.
Great Deal 
New Comment