Gelomyrtol Forte 2x20 Capsules

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Jeigu esate nėščia, žindote kūdikį, manote, kad galbūt esate nėščia, arba planuojate pastoti, tai prieš vartodama šį vaistą, pasitarkite su gydytoju arba vaistininku. Gelomyrtol, a phytomedicine, is extracted from the leaves of Myrtaceae. It has been shown to have secretolytic, mucolytic, secretomotoric, and anti-inflammatory properties. [12–15] The efficacy of Gelomyrtol in the treatment of acute or chronic sinusitis has been confirmed in randomized controlled trials (RCTs) and recommended in German and international treatment guidelines. [16,17] Therefore, Gelomyrtol has the potential to be an effective adjuvant therapy for acute or chronic sinusitis. However, there is little evidence of its curative efficacy for acute or chronic sinusitis. Therefore, the aim of this study is to provide a comprehensive systematic review on the safety and efficacy of Gelomyrtol for patients with acute or chronic sinusitis. 1.1 Review objectives

Retais atvejais gali pasireikšti padidėjusio jautrumo reakcijos (pvz., odos bėrimas, niežulys, veido patinimas, dusulys arba kraujotakos sutrikimas). Jeigu sergate bronchų astma, kokliušu arba kitokia kvėpavimo takų liga pasižyminčia padidėjusiu kvėpavimo sistemos jautrumu, Gelomyrtol ar Gelomyrtol forte galima vartoti tik gydytojui paskyrus. In one double-blind, placebo-controlled trial, patients with a history of sinusitis episodes and acute rhinosinusitis at the time of enrolment were randomized to receive either MFNS 400 μg twice daily ( n = 200) or placebo ( n = 207) as adjunctive treatments to amoxicillin for 21 days [ 46]. The mean decrease in total symptom score (TSS) from baseline to Day 15 – the primary endpoint – was greater in the MFNS group (5.87) than in the placebo group (5.05) ( p ≤ 0.01). The decrease in TSS from Day 16 to Day 21 was also higher in the MFNS group (7.90) than in the placebo group (6.52) (p ≤ 0.01). Individual symptoms such as congestion, facial pain or headache improved significantly more with MFNS than with placebo from Day 16 to Day 21. However, symptoms such as rhinorrhea, post-nasal drip, or cough were not significantly different between the MFNS and placebo groups. In both treatment groups, most adverse events were mild or moderate. Bachert C, Thakur M, Weyers S, Bittner C, Abramov-Sommariva D. Reporting clinical trial results of phytomedicines in acute rhinosinusitis: letter to the editor regarding Gottschlich S, Roschmann K, Candler H. Adv Ther (2018); 35:1023-1034. doi: 10.1007/s12325-018-0736-7. Adv Ther. 2019;36:1011–3. https://doi.org/10.1007/s12325-019-00933-6. Marz RW, Ismail C, Popp MA. Profile and effectiveness of a phytogenic combination preparation for treatment of sinusitis. Wien Med Wochenschr. 1999;149:202–8.jei yra alergija eukalipto aliejui, saldžiųjų apelsinų aliejui, mirtos aliejui, citrinos aliejui arba cineolui (svarbiausiam eukalipto aliejaus komponentui) arba bet kuriai pagalbinei šio vaisto medžiagai (jos išvardytos 6 skyriuje); Labai didelių dozių sukeliamas centrinės nervų sistemos veiklos ir lokomotorinio aktyvumo slopinimas galbūt vyksta dėl nespecifinio vaisto poveikio membranoms (pasireiškiančio centrinės nervų sistemos struktūrų slopinimu). Manoma, kad diurezės padidėjimą lemia spartesnė glomerulų filtracija, kurią sukelia intensyvesnė inkstų kraujotaka. Poveikis lygiesiems raumenims partvirtintas poveikio virškinimo traktui tyrimais (nustatytas motorikos susilpnėjimas). Pastebėtas skrandžio sulčių susidarymo slopinimas, tačiau farmakologiškai tai nepaaiškinama. Neveikia širdies ir kraujagyslių sistemos bei kvėpavimo sistemos funkcijos. Tesche and colleagues conducted a double-blind randomized trial comparing a herbal preparation containing five components, possibly resembling Sinupret, with cineole [ 43]. Of note, this study did not clearly state using Sinupret when refering to the composition of the preparation. Furthermore, no placebo group was included in the study. The study recruited a total of 150 patients across three centres, with 75 patients randomized to each treatment group. Two capsules containing 200 mg of cineole were given three times daily and one tablet of the 5-component herbal preparation was given three times daily. Each treatment was given for 7 days and a spray of xylometazoline was given as concomitant medication to alleviate nasal obstruction. The purely herbal active ingredient works like an inhalation from the inside. The natural self-cleaning powers of the airways are activated: The mucus in the bronchi and paranasal sinuses is loosened, the bronchi relax and the pathogens are fought. Frees the airways - shortens the duration of the illness. PubMed, EMBASE, the Cochrane Library, the Web of Science, the Chinese National Knowledge Infrastructure Database, the Chinese Biomedical Literature Database, the Wan Fang Database, and the Chongqing VIP Chinese Science, and Technology Periodical Database will be searched from their commencement until July 2020. Randomized controlled trials of Gelomyrtol for acute or chronic sinusitis will be selected in any language. Primary outcomes will include the Sino-Nasal Outcome Test-22 (SNOT-22) score, quality of life score as measured by SF-36, and the change in computed tomography (CT) score. Study selection, data extraction, and deviation risk assessment will be carried out by 2 investigators independently. RevMan V.5.3 software will be used to analyze the study data. Results:

Visada vartokite šį vaistą tiksliai kaip nurodė gydytojas arba vaistininkas. Jeigu abejojate, kreipkitės į gydytoją arba vaistininką. Gelomyrtol has been proved to have the effects of anti-inflammation, dilution of mucus, and so on. Its curative effect has been confirmed. However, the efficacy and safety of Gelomyrtol in the treatment of acute or chronic sinusitis are not clear. Therefore, we believe that the results of this meta-analysis will provide some reference for clinicians and researchers. 3.1 AmendmentsNot just in interaction with flu-like infections, but also as a result of one allergic rhinitis Sinus infection can occur. This is usually accompanied by an annoying pressure pain and throbbing around the cheekbones, forehead and eyes, but can also radiate into the ears.

Lizogub VG, Riley DS, Heger M. Efficacy of a pelargonium sidoides preparation in patients with the common cold: a randomized, double blind, placebo-controlled clinical trial. Explore (NY). 2007;3:573–84. https://doi.org/10.1016/j.explore.2007.09.004. Cough and sputum are typical signs of bronchitis. This is considered chronic if symptoms persist on most days for at least three months per year for two consecutive years. It is also suitable Gelomyrtol, used to treat bronchitis. The herbal expectorant can also be combined with antibiotics. Always ask your doctor or pharmacist about the tolerance and effectiveness of GeloMyrtol. What is bronchitis? Schoetz K, Erdelmeier C, Germer S, Hauer H. A detailed view on the constituents of EPs 7630. Planta Med. 2008;74:667–74. https://doi.org/10.1055/s-2008-1074515. Another study compared a combination of Sinupret and Cinnabaris 3X with synthetic treatment, including antibiotics, secretolytics and sympathomimetics in patients presenting with acute sinusitis or an acute exacerbation of a chronically relapsing sinusitis [ 17]. Although treatment differences varied depending on the endpoint, differences were not clinically relevant. The study was limited by its non-randomized design and the fact that study groups were not evenly matched before treatment administration, with the authors concluding that ‘randomized trials including at least 400 patients are needed to produce valid results’.

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In summary, adequately powered randomized trials have demonstrated superiority of Sinupret versus placebo in patients with bacterial or viral rhinosinusitis. Trials of Sinupret in bacterial sinusitis almost exclusively included male patients, while trials of Sinupret in viral sinusitis included a mixed-gender study population. Sinupret versus other treatments Meister R, Wittig T, Beuscher N, de Mey C. Efficacy and tolerability of myrtol standardized in long-term treatment of chronic bronchitis. A double-blind, placebo-controlled study. Study Group Investigators. Arzneimittelforschung. 1999;49:351–8. https://doi.org/10.1055/s-0031-1300426. This systematic review will explore whether Gelomyrtol is an effective and safe intervention in the treatment of acute or chronic sinusitis. Ethics and dissemination: